Johns Hopkins CBID – Jhpiego Emergency Zika Design Challenge

Kick-off meeting: Thursday, April 7, 2016, 5:00pm to 9:00pm
Design Challenge: Saturday, April 9, 2016 from 9:00am, ending Sunday, April 10, 2016 at 3:00 PM (EDT)
Baltimore, MD

 

Zika-Heat-3The Johns Hopkins University Center for Bioengineering Innovation & Design (CBID) and Jhpiego invite you to take part in a weekend design challenge to focus in the prevention of mosquito bites in an effort to reduce the spread of the Zika virus. Despite significant efforts and technological advancements, mosquitoes continue to pose considerable public health problems across wide geographical areas. The public health cost is enormous. There is a recent associating between Zika virus infection and microcephaly in infants born to women infected during pregnancy and Guillain-Barre syndrome in Zika-infected individuals. New ideas and designs can help save lives. YOU can help save lives!

Mosquitoes are responsible for a variety of diseases, including malaria, dengue, chikungunya, and Zika. Current best practices for personal protection against mosquito bites are avoidance and include the following major categories: 1) Topical insect repellants; 2) Protective clothing, including insecticide-treated clothing; 3) Bed nets and insecticide-treated nets; 4) Screens, mesh, or net on windows and doors. Other solutions that are available but have shown to be less effective for personal protection are: 5) Spatial repellents such as coils, emanators, and insecticide knockdown sprays; and 6) air conditioning and fans.

While the mortality rate if Zika is low, there is still an urgent responsibility to protect those vulnerable to the disease and other diseases transmitted by mosquitoes. This event is one of the MANY ways Johns Hopkins is doing its part. It is an opportunity for YOU to contribute to a part of the solution.

Who:
Any Johns Hopkins student, fellow, faculty member, clinicians, administrator, and staff may apply. Skill sets that we are looking for include (but not limited to):
• Residents/ fellows, especially with infectious disease control and vector control experience
• Public Health students/ professionals with experience in infectious disease and epidemiology, global health interventions
• Biomedical Engineers
• Industrial Design & Human Factors Engineers
• Materials Scientists with expertise in films, coatings, etc
• Soft-goods designers (outdoor goods, clothing, etc)
• Anyone with experience in mosquito vector control or has ideas about how to avoid being bitten, or understands insecticides, repellents or other methods of repelling bugs
• Highly creative and inventive people of all backgrounds

Schedule:

Between NOW and Thursday, April 7:  Read the materials at the links in this announcement (BELOW), and do your own research and capture your own ideas

Immediately: REGISTER — REQUIRED! By registering, you agree to the ground rules of this Design Challenge (BELOW) and commit to attending. We will have a badge made for you allowing entry to the Design Studio and for meals.

Thursday, April 7, 5PM – 9PM: Arrive on time to kick off the Live Learning Session. Featured will be experts from around the world in various topics related to this disease and global responses to it. The kick-off will include demonstrations of current technologies and actual products to help you get up to speed quickly and prepared to help design better solutions. We will help you create a team, or just come as a team.

Friday, April 8: Explore new ideas on your own! No event will take place but this day gives participants time to brainstorm and work with their teams to develop their concept.

Saturday, April 10, 9 AM – 6 PM: Think — Discuss — Create — Build. Working in teams, explore the specific sub-challenges outlined on Friday. Develop insights into causes of some of the weaknesses of existing designs. Create solutions or elements of a solution. Build, sew, glue, draw, these ideas and vet them with the experts present.

Sunday, April 11, 9AM – 3PM: Create — Build — Refine — Share. Refine and expand your ideas, throw some out, improve on others, document your ideas and submit them to our review panel. Special recognition will be given to the top teams as well.

Ground Rules:
• Please respect the equipment, supplies and personnel in the Design Studio.
• Each team or individuals should document their idea in the form provided and submit online during the event. Judges will use these to decide on awards.
• Some of the ideas submitted may be selected to include in proposals by CBID and Jhpiego for funding for further development of your solutions. If your idea (based on the forms submitted) is included in one of these proposals and funding for development is obtained, you will be invited to participate in the development project.
• All IP contained in the idea submission forms will be the property or deemed assigned to Johns Hopkins University, and will be managed according to the established IP rules of JHU.
• Only people registered may attend. Registration closes Wednesday at 6pm.
• Food and drink will be provided (dinner Friday, breakfast and lunch Saturday & Sunday)

For further questions, please contact:

• Aditya Polsani, Director, Business Development

Links for background reading and videos:

Information Reading & Research
• CDC. Zika Virus Overview. http://www.cdc.gov/media/dpk/2016/dpk-zika-virus.html

• New York Times. Short Answers to Hard Questions about Zika Virus. http://www.nytimes.com/interactive/2016/health/what-is-zika-virus.html?_r=0

• WHO. Pregnancy management in the context of Zika virus: Interim guidance. 2016.
http://www.who.int/csr/resources/publications/zika/pregnancy-management/en/

• Lupi E, Hatz C, Schlagenhauf P. The efficacy of repellents against Aedes, Anopheles, Culex and Ixodes spp. – a literature review. Travel Med Infect Dis. 2013 Nov-Dec;11(6):374-411. http://www.travelmedicinejournal.com/article/S1477-8939(13)00173-7/pdf

• Rodrigeuez, SD et al. The Efficacy of Some Commercially Available Insect Repellents for Aedes aegypti (Diptera: Culicidae) and Aedes albopictus (Diptera: Culicidae) Insect Sci. (2015) 15(1): 140. http://jinsectscience.oxfordjournals.org/content/15/1/140

• Pennetier C, Chabi J, Martin T, Chandre F, Rogier C, Hougard JM, Pages F. New protective battle-dress impregnated against mosquito vector bites. Parasit Vectors. 2010 Sep 1;3:81. doi: 10.1186/1756-3305-3-81. http://parasitesandvectors.biomedcentral.com/articles/10.1186/1756-3305-3-81

• Berniera UR, Pablo Gurman, Gary G. Clark, Noel Elman. Functional Micro-Dispensers based on Micro-Electro-Mechanical-Systems (MEMS) integrated with fabrics as functional materials to protect humans from mosquito feeding. Journal of Controlled Release. Volume 220, Part A, 28 December 2015, Pages 1–4.
http://www.sciencedirect.com/science/article/pii/S0168365915301498

http://www.who.int/water_sanitation_health/resources/en/vector059to87.pdf

• Sochantha T. et al. Personal protection by long-lasting insecticidal hammocks against the bites of forest malaria vectors. Trop Med Int Health. 2010 Mar;15(3):336-41. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-3156.2009.02457.x/full

• Graham K. et al. Insecticide-treated plastic tarpaulins for control of malaria vectors in refugee camps. Med Vet Entomol. 2002 Dec;16(4):404-8.

http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2915.2002.00395.x/full

• Rowland, M, et al. Permethrin-treated chaddars and top-sheets: Appropriate technology for protection against malaria in Afghanistan and other complex emergencies. Trans R Soc Trop Med Hyg (September-October 1999) 93 (5): 465-472. http://trstmh.oxfordjournals.org/content/93/5/465.abstract

• Bernier UR, Clark GG, Gurman P, Elman NM. The Use of Microdispensers with Spatial Repellents for Personal Protection against Mosquito Biting. J Med Entomol. 2015 Dec 4. pii: tjv190. http://www.ncbi.nlm.nih.gov/pubmed/26637385

• Andrés M, Lena M Lorenz, Edgar Mbeleya and Sarah J Moore. Modified mosquito landing boxes dispensing transfluthrin provide effective protection against Anopheles arabiensis mosquitoes under simulated outdoor conditions in a semi-field system. Malaria Journal201514:255. https://malariajournal.biomedcentral.com/articles/10.1186/s12936-015-0762-8

• Govella NJ, Ogoma SB, Paliga J, Chaki PP, Killeen G. Impregnating hessian strips with the volatile pyrethroid transfluthrin prevents outdoor exposure to vectors of malaria and lymphatic filariasis in urban Dar es Salaam, Tanzania. Parasit Vectors. 2015 Jun 12;8:322. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465323/

• Pates HV, Line JD, Keto AJ, Miller JE. Personal protection against mosquitoes in Dar es Salaam, Tanzania, by using a kerosene oil lamp to vaporize transfluthrin. Med Vet Entomol. 2002 Sep;16(3):277-84. http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2915.2002.00375.x/epdf

https://www.epa.gov/insect-repellents/repellent-treated-clothing

• Lupi E, Hatz C, Schlagenhauf P. The efficacy of repellents against Aedes, Anopheles, Culex and Ixodes spp. – a literature review. Travel Med Infect Dis. 2013 Nov-Dec;11(6):374-411. http://www.travelmedicinejournal.com/article/S1477-8939(13)00173-7/pdf

• Debboun M, D. Strickman. Insect repellents and associated personal protection for a reduction in human disease. Medical and Veterinary Entomology Volume 27, Issue 1, pages 1–9, March 2013. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2915.2012.01020.x/epdf

https://en.wikipedia.org/wiki/Mosquito_laser

• Enayati AA, Hemingway J, Garner P. Electronic mosquito repellents for preventing mosquito bites and malaria infection. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD005434. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005434.pub2/abstract

• Revay EE, Junnila A, Xue RD, Kline DL, Bernier UR, Kravchenko VD, Qualls WA, Ghattas N, Müller GC. Evaluation of commercial products for personal protection against mosquitoes. Acta Trop. 2013 Feb;125(2):226-30. doi: 10.1016/j.actatropica.2012.10.009. Epub 2012 Oct 22. http://www.sciencedirect.com/science/article/pii/S0001706X12003452

• Ribas J and AM CarreñoII. Evaluation of the use of repellent against mosquito bite by military personnel in the Amazon Basin. An. Bras. Dermatol. vol.85 no.1 Rio de Janeiro Jan./Feb. 2010. http://www.scielo.br/scielo.php?pid=S0365-05962010000100004&script=sci_arttext&tlng=en

• Ives AR, Paskewitz SM; Inter-L&S 101; Biology Interest Groups; Entomology Class 201. Testing vitamin B as a home remedy against mosquitoes. J Am Mosq Control Assoc. 2005 Jun;21(2):213-7. http://www.bioone.org/doi/10.2987/8756-971X(2005)21[213:TVBAAH]2.0.CO;2?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

 

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